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The Impact of Biomaterial Charge on Cells Bioelectrical Signaling

The Impact of Biomaterial Charge on Cells’ Bioelectrical Signaling

June 2026

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nanofibrous-composite-hydrogels-for-modulating-stem-cell-behavior.jpg

Nanofibrous-Composite Hydrogels for Modulating Stem Cell Behavior

April 2026

Andres F Roca-Arroyo, Jhonatan A Gutierrez-Rivera, Laura M Mejia-Rosales, Logan D Morton, David A Castilla-Casadiego
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collagen-nanofiber-alignment-attenuates-leader-follower-energetic-and-metabolic-differences-during-collective-migration-in-pancreatic-cancer.jpg

Collagen nanofiber alignment attenuates leader-follower energetic and metabolic differences during collective migration in pancreatic cancer

January 2026

Madison R Pickett, Mohini Kamra, David A Castilla-Casadiego, William Matsui, Adrianne M Rosales, Janet Zoldan, Sapun H Parekh
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development-of-a-low-cost-electrospinning-system-with-a-bidirectional-collector-for-uniform-nanofibrous-membranes.jpg

Development of a low-cost electrospinning system with a bidirectional collector for uniform nanofibrous membranes

December 2025

Jhonatan A Gutierrez-Rivera, Andres F Roca-Arroyo, David A Castilla-Casadiego, Alberto Albis
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lyophilized-drug-reservoir-integrated-hydrogel-forming-microarray-patches-for-transdermal-delivery-of-isoniazid-and-pyridoxine-hydrochloride-as-a-strategy-to-treat-latent-tuberculosis.jpg

Lyophilized drug reservoir-integrated hydrogel-forming microarray patches for transdermal delivery of isoniazid and pyridoxine hydrochloride as a strategy to treat latent tuberculosis

October 2025

Maria J Rey-Sanchez, Katherine A Miranda-Muñoz, Logan D Morton, Gabriel J Rodriguez-Rivera, David A Castilla-Casadiego
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hydrogel-network-architecture-design-space-impact-on-mechanical-and-viscoelastic-properties.jpg

Hydrogel Network Architecture Design Space: Impact on Mechanical and Viscoelastic Properties

July 2025

Andres F Roca-Arroyo, Jhonatan A Gutierrez-Rivera, Logan D Morton, David A Castilla-Casadiego
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tunable-hydrogel-networks-by-varying-secondary-structures-of-hydrophilic-peptoids-provide-viable-3d-cell-culture-platforms-for-hmscs.jpg

Tunable hydrogel networks by varying secondary structures of hydrophilic peptoids provide viable 3D cell culture platforms for hMSCs

May 2025

Aldaly Pineda-Hernandez, David A Castilla-Casadiego, Logan D Morton, Sebastian A Giordano-Nguyen, Kathleen N Halwachs, Adrianne M Rosales
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stimuli-responsive-substrates-to-control-the-immunomodulatory-potential-of-stromal-cells.jpg

Stimuli-Responsive Substrates to Control the Immunomodulatory Potential of Stromal Cells

September 2024

David A Castilla-Casadiego, Darren H Loh, Aldaly Pineda-Hernandez, Adrianne M Rosales
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peptoid-cross-linked-hydrogel-stiffness-modulates-human-mesenchymal-stromal-cell-immunoregulatory-potential-in-the-presence-of-interferon-gamma.jpg

Peptoid-Cross-Linked Hydrogel Stiffness Modulates Human Mesenchymal Stromal Cell Immunoregulatory Potential in the Presence of Interferon-Gamma

April 2024

David A Castilla‐Casadiego, Logan D Morton, Darren H Loh, Aldaly Pineda‐Hernandez, Ajay P Chavda, Francis Garcia, Adrianne M Rosales
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crosslinker-structure-modulates-bulk-mechanical-properties-and-dictates-hmsc-behavior-on-hyaluronic-acid-hydrogels.jpg

Crosslinker structure modulates bulk mechanical properties and dictates hMSC behavior on hyaluronic acid hydrogels

January 2023

Logan D Morton, David A Castilla-Casadiego, Ajay C Palmer, Adrianne M Rosales
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biodegradable-microneedle-patch-for-delivery-of-meloxicam-for-managing-pain-in-cattle.jpg

Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle

August 2022

David A Castilla-Casadiego, Katherine A Miranda-Muñoz, Jesse L Roberts, Anne D Crowell, David Gonzalez-Nino, Dipankar Choudhury, Frank O Aparicio-Solis, Shannon L Servoss, Adrianne M Rosales, Gary Prinz, Min Zou, Yuntao Zhang, Johann F Coetzee, Lauren F Greenlee, Jeremy Powell, Jorge Almodovar
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immunomodulatory-functions-of-human-mesenchymal-stromal-cells-are-enhanced-when-cultured-on-hep-col-multilayers-supplemented-with-interferon-gamma.jpg

Immunomodulatory functions of human mesenchymal stromal cells are enhanced when cultured on HEP/COL multilayers supplemented with interferon-gamma

January 2022

Mahsa Haseli, David A Castilla-Casadiego, Luis Pinzon-Herrera, Alexander Hillsley, Katherine A Miranda-Munoz, Srikanth Sivaraman, Adrianne M Rosales, Raj R Rao, Jorge Almodovar
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design-characterization-and-modeling-of-a-chitosan-microneedle-patch-for-transdermal-delivery-of-meloxicam-as-a-pain-management-strategy-for-use-in-cattle.jpg

Design, characterization, and modeling of a chitosan microneedle patch for transdermal delivery of meloxicam as a pain management strategy for use in cattle

January 2021

David A Castilla-Casadiego, Hayden Carlton, David Gonzalez-Nino, Katherine A Miranda-Muñoz, Raheleh Daneshpour, David Huitink, Gary Prinz, Jeremy Powell, Lauren Greenlee, Jorge Almodovar
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methods-for-the-assembly-and-characterization-of-polyelectrolyte-multilayers-as-microenvironments-to-modulate-human-mesenchymal-stromal-cell-response.jpg

Methods for the Assembly and Characterization of Polyelectrolyte Multilayers as Microenvironments to Modulate Human Mesenchymal Stromal Cell Response

November 2020

David A Castilla-Casadiego, Hemanta Timsina, Mahsa Haseli, Luis Pinzon-Herrera, Yu-Hsuan Chiao, S Ranil Wickramasinghe, Jorge Almodovar
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high-performance-polyacrylic-acid-grafted-pvdf-nanofiltration-membrane-with-good-antifouling-property-for-the-textile-industry.jpg

High-Performance Polyacrylic Acid-Grafted PVDF Nanofiltration Membrane with Good Antifouling Property for the Textile Industry

October 2020

Yu-Hsuan Chiao, Shu-Ting Chen, Micah Belle Marie Yap Ang, Tanmoy Patra, David Alfonso Castilla-Casadiego, Rong Fan, Jorge Almodovar, Wei-Song Hung, S Ranil Wickramasinghe
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heparin-collagen-surface-coatings-modulate-the-growth-secretome-and-morphology-of-human-mesenchymal-stromal-cell-response-to-interferon-gamma.jpg

Heparin/collagen surface coatings modulate the growth, secretome, and morphology of human mesenchymal stromal cell response to interferon-gamma

August 2020

Said J Cifuentes, Priyanka Priyadarshani, David A Castilla‐Casadiego, Luke J Mortensen, Jorge Almodóvar, Maribella Domenech
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real-time-monitoring-of-human-schwann-cells-on-heparin-collagen-coatings-reveals-enhanced-adhesion-and-growth-factor-response.jpg

Real-time monitoring of human Schwann cells on heparin-collagen coatings reveals enhanced adhesion and growth factor response

August 2020

Luis Pinzon-Herrera, Janet Mendez-Vega, Adriana Mulero-Russe, David A Castilla-Casadiego, Jorge Almodovar
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effects-of-physical-chemical-and-biological-stimulus-on-h-msc-expansion-and-their-functional-characteristics.jpg

Effects of Physical, Chemical, and Biological Stimulus on h-MSC Expansion and Their Functional Characteristics

November 2019

David A Castilla-Casadiego, Ana M Reyes-Ramos, Maribella Domenech, Jorge Almodovar
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heparin_collagen-coatings-improve-human-mesenchymal-stromal-cell-response-to-interferon-gamma.jpg

Heparin/Collagen Coatings Improve Human Mesenchymal Stromal Cell Response to Interferon Gamma

May 2019

David A Castilla-Casadiego, José R García, Andrés J García, Jorge Almodovar
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simultaneous-characterization-of-physical-chemical-and-thermal-properties-of-polymeric-multilayers-using-infrared-spectroscopic-ellipsometry.jpg

Simultaneous characterization of physical, chemical, and thermal properties of polymeric multilayers using infrared spectroscopic ellipsometry

September 2018

David A Castilla-Casadiego, Luis Pinzon-Herrera, Maritza Perez-Perez, Beatriz A Quiñones-Colón, David Suleiman, Jorge Almodovar
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aptamer-based-impedimetric-assay-of-arsenite-in-water-interfacial-properties-and-performance.jpg

Aptamer-Based Impedimetric Assay of Arsenite in Water: Interfacial Properties and Performance

February 2018

Karlene Vega-Figueroa, Jaime Santillán, Valerie Ortiz-Gómez, Edwin O Ortiz-Quiles, Beatriz A Quiñones-Colón, David A Castilla-Casadiego, Jorge Almodóvar, Marvin J Bayro, José A Rodríguez-Martínez, Eduardo Nicolau
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green-electrospinning-of-a-collagenhydroxyapatite-composite-nanofibrous-scaffold.jpg

“Green” electrospinning of a collagen/hydroxyapatite composite nanofibrous scaffold

September 2016

David A Castilla-Casadiego, Michael Maldonado, Paul Sundaram, Jorge Almodovar
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engineering-of-a-stable-collagen-nanofibrous-scaffold-with-tunable-fiber-diameter-alignment-and-mechanical-properties.jpg

Engineering of a Stable Collagen Nanofibrous Scaffold with Tunable Fiber Diameter, Alignment, and Mechanical Properties

June 2016

David A Castilla‐Casadiego, Heleine V Ramos‐Avilez, Stephany Herrera‐Posada, Barbara Calcagno, Luis Loyo, Jacoby Shipmon, Aldo Acevedo, Anibal Quintana, Jorge Almodovar
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evaluation-of-culture-conditions-to-obtain-fatty-acids-from-saline-microalgae-species-dunaliella-salina-sinecosyfis-sp-and-chroomonas-sp.jpg

Evaluation of Culture Conditions to Obtain Fatty Acids from Saline Microalgae Species: Dunaliella salina, Sinecosyfis sp., and Chroomonas sp.

June 2016

DA Castilla Casadiego, AR Albis Arrieta, ER Angulo Mercado, SJ Cervera Cahuana, KS Baquero Noriega, AF Suárez Escobar, ED Morales Avendaño
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